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Important safety information

PRASCEND is for use in horses only. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. Weight loss, lack of energy, and behavioral changes also may be observed. If severe, a temporary dose reduction may be necessary. PRASCEND has not been evaluated in breeding, pregnant, or lactating horses and may interfere with reproductive hormones in these horses. PRASCEND Tablets should not be crushed due to the potential for increased human exposure. Refer to package insert for complete product information.

Benefits of early treatment

When it comes to treating PPID, the earlier the better. Although some early signs can be managed (eg, extra clipping and grooming will control hypertrichosis), a case can be made in support of starting medical treatment when clinical signs are initially recognized.2 Early treatment can minimize progression of PPID and prolong the life of the horse.2
When caught early, PPID treatment is very successful in reducing common signs and allowing affected horses to live normal lives.2 Even when a horse has advanced disease, treatment usually gives him a longer, healthier life.3

Regular Veterinary Visits

If you are caring for a horse who has been diagnosed with PPID, scheduling regular veterinary visits is important. Your veterinarian will regularly check on your horse to ensure proper dosing and that clinical signs are not advancing. Working with your veterinarian is key to managing PPID.

Helpful Tips for Managing PPID

As a horse owner, you can play a key role in keeping your horse healthy and active at any age. Visit with your veterinarian about a treatment plan but a few simple steps you can take to ensure your horse is in the best health possible include:

  • Regular hoof care
  • Dental exams
  • Body clipping
  • Diet management (speak with your veterinarian about the best nutrition protocol)
  • Use feeds that are easy to chew and digest
  • Provide plenty of fresh water
  • Deworm regularly
  • Properly vaccinate your horse

Diet and exercise

Your veterinarian will advise you on a customized diet and exercise plan that will help your horse maintain the correct weight. Horses with PPID often do well on the low-sugar, low-starch diets if considered to be prone to laminitis.3


1. PRASCEND® (pergolide tablets) [Freedom of Information Summary]. St. Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2011.
2. Schott HC. Pars pituitary intermedia dysfunction: challenges of diagnosis and treatment. In: Proceedings from the 52nd American Association of Equine Practitioners Annual Convention; December 2-6, 2006; San Antonio, TX.
3. McFarlane D. equine pituitary pars intermedia dysfunction. Vet Clin North Am Equine Pract. 2011;27(1):93–113