Watch for early signs, and your horse's future should be bright.

When it comes to treating PPID, the earlier the better. The disease progresses slowly, so signs may be hidden at first, delaying diagnosis. Some lesser known, but commonly missed, early signs include delayed shedding of winter coat hairs, changes in coat color, increased hunger, loss of muscle mass, and unexplained laminitis.

Keep your eyes peeled for these and other signs. If you see any signs, get in touch with your veterinarian about care and treatment options. He or she may recommend immediate treatment for the best chance of getting your horse back to himself again.

When caught early, PPID treatment is very successful in reducing common signs and allowing affected horses to live normal lives.1 Even when a horse has an advanced stage of the disease, treatment usually leads to a longer, healthier life.1

Learn more about PPID treatment considerations.

Click here to read some helpful hints on caring for a horse with PPID.

Click here to download further information to help your horse get the best results from PPID treatment.

Click here to join Partners in PPID for Horse Owners now. It’s free!

Important safety information

PRASCEND is for use in horses only. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. Weight loss, lack of energy, and behavioral changes also may be observed. If severe, a temporary dose reduction may be necessary. PRASCEND has not been evaluated in breeding, pregnant, or lactating horses and may interfere with reproductive hormones in these horses. Using PRASCEND at the same time as drugs known as dopamine antagonists should be avoided. These drugs may diminish the effectiveness of PRASCEND. If your horse is especially sensitive to pergolide mesylate or similar products, PRASCEND should not be used. Refer to the package insert for complete product information.


  1. PRASCEND® (pergolide mesylate) [Freedom of Information Summary]. St. Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2011.