Now you can reduce the signs of PPID and help him get back to normal1

PPID, which stands for pituitary pars intermedia dysfunction and is more commonly known as equine Cushing's disease, can make horses seem older than they really are and increase their risk for dangerous conditions like laminitis.2 PRASCEND is the first and only FDA-approved product for the management of PPID in horses.1 It can reduce signs, like fat in unusual places or an abnormal hair coat, so horses can look and feel like their healthy, happy selves again.1

Talk to your veterinarian to see if PRASCEND is right for your horse or click here to learn more.

This website is only intended for residents of the United States.

How old was your horse when it was diagnosed with PPID?

Important safety information

PRASCEND is for use in horses only. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. Weight loss, lack of energy, and behavioral changes also may be observed. If severe, a temporary dose reduction may be necessary. PRASCEND has not been evaluated in breeding, pregnant, or lactating horses and may interfere with reproductive hormones in these horses. Using PRASCEND at the same time as drugs known as dopamine antagonists should be avoided. These drugs may diminish the effectiveness of PRASCEND. If your horse is especially sensitive to pergolide mesylate or similar products, PRASCEND should not be used. Refer to the package insert for complete product information.


  1. Donaldson MT, McDonnell SM, Schanbacher BJ, Lamb SV, McFarlane D, Beech J. Variation in plasma adrenocorticotropic hormone concentration and dexamethasone suppression test results with season, age, and sex in healthy ponies and horses. J Vet Intern Med. 2005;19(2):217-222.
  2. McGowan TW, Hodgson DR, McGowan CM. The prevalence of equine Cushing's syndrome in aged horses. In: Proceedings from the 25th American College of Veterinary Internal Medicine Forum; June 6-9, 2007; Seattle, WA. Abstract 603.
  3. Oke S. Equine Cushing's disease [fact sheet]. Beech J, ed.The Horse: Your Guide to Equine Health Care. Lexington, KY: Blood-Horse Publications; 2010. Available at: Accessed August 12, 2011.
  4. Schott HC. Pars pituitary intermedia dysfunction: challenges of diagnosis and treatment. In: Proceedings from the 52nd American Association of Equine Practitioners Annual Convention; December 2-6, 2006; San Antonio, TX.